Evaluation of enzyme inhibitors in drug discovery : (Record no. 115204)

MARC details
000 -LEADER
fixed length control field 02449cam a22003257i 4500
001 - CONTROL NUMBER
control field 19095378
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 210916t2013 enka b 001 0 eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781118488133 :
Terms of availability 6,990
040 ## - CATALOGING SOURCE
Original cataloging agency BSRU
082 00 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 615.19
Item number C782E 2013
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Copeland, Robert Allen
245 10 - TITLE STATEMENT
Title Evaluation of enzyme inhibitors in drug discovery :
Remainder of title a guide for medicinal chemists and pharmacologists /
Statement of responsibility, etc. Robert A. Copeland
250 ## - EDITION STATEMENT
Edition statement 2nd ed.
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Hoboken, N.J. :
Name of publisher, distributor, etc. Wiley,
Date of publication, distribution, etc. 2013
300 ## - PHYSICAL DESCRIPTION
Extent xxx, 538 p.
Other physical details ill. ;
Dimensions 22 cm.
490 1# - SERIES STATEMENT
Series statement Green chemistry
504 ## - BIBLIOGRAPHY, ETC. NOTE
Bibliography, etc. note Includes bibliographical references and index.
520 ## - SUMMARY, ETC.
Summary, etc. There has been explosive growth in the hunt for new pharmaceutically agents globally. Traditionally, this has been the purview of the pharmaceutical industry, but today, this effort crosses academic, government, and industry laboratories across the world. Enzymes remain the most valued and common of drug targets; hence, a detailed understanding of their interactions with inhibitors is critical to successful drug discovery. This book provides a practical, readable, and comprehensive treatment of these topics that allows scientists to master the art of applied enzymology for drug discovery. The book addresses the opportunities for inhibitor interactions with enzyme targets arising from consideration of the catalytic reaction mechanism; discusses how inhibitors are properly evaluated for potency, selectivity, and mode of action, covers the potential advantages and liabilities of specific inhibition modalities with respect to efficacy invivo, and provides valuable biochemical insights to help medicinal chemists and pharmacologists most effectively pursue lead optimization. It includes two new chapters, one on the pioneering idea of drug-target residence time fostered by Dr. Copeland, and the second on quantitative biochemistry. Five new appendices are added
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Enzyme inhibitors
General subdivision Therapeutic use
-- Testing
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Drugs
General subdivision Design
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Chemical engineering
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title Green chemistry
856 4# - ELECTRONIC LOCATION AND ACCESS
Materials specified ดูปกและสารบัญ (see cover and contents)
Uniform Resource Identifier https://opacb.bsru.ac.th/book/File115204.pdf
900 ## - EQUIVALENCE OR CROSS-REFERENCE-PERSONAL NAME [LOCAL, CANADA]
Personal name 21/10/26
901 ## - LOCAL DATA ELEMENT A, LDA (RLIN)
a Chem.
901 ## - LOCAL DATA ELEMENT A, LDA (RLIN)
a new_oct21
940 ## - EQUIVALENCE OR CROSS-REFERENCE--UNIFORM TITLE [OBSOLETE] [CAN/MARC only]
Uniform title 31319 ห้องสมุด
-- 31320 C.2 บัณฑิต
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Koha item type General Books
039 ## -
-- 1
-- STAFF MATRIX
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Collection code Home library Current library Shelving location Date acquired Total Checkouts Full call number Barcode Date last seen Copy number Price effective from Koha item type
        Available for Loans Non-fiction สำนักวิทยบริการ (Center) สำนักวิทยบริการ (Center) ชั้น 7 หนังสือทั่วไปภาษาอังกฤษ 000-900 26/10/2021   615.19 C782E 2013 3000027810 26/10/2021 1 26/10/2021 General Books